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Mechanisms of resistance to chlorambucil in chronic lymphocytic leukemia

โœ Scribed by Asher Begleiter; Gerald J. Goldenberg; Cynthia D. Anhalt; Kristine Lee; Michael R.A. Mowat; Lyonel G. Israels; James B. Johnston


Book ID
113239348
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
777 KB
Volume
15
Category
Article
ISSN
0145-2126

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The effect of early therapy on the course of chronic lymphocytic leukemia (CLL) has not been established. Fifty-nine patients with indolent Rai stage I and II CLL were randomized to receive intermittent chlorambucil once a month or to receive no treatment. The two groups were comparable in entry cha