Glutathione S-transferases (GSTs) are metabolic phase II enzymes that promote reactive metabolite elimination by conjugating them to glutathione (GSH). Because of their important role in xenobiotic metabolism and detoxification, they have been implicated in carcinogenesis processes, especially epith
β¦ LIBER β¦
P198 Transcriptome based prediction of the response to neoadjuvant chemotherapy of head and neck squamous cell carcinoma
β Scribed by Tomkiewicz, C.; Hans, S.; Agier, N.; Marisa, L.; Mucchielli-Giorgi, M.H.; Imbeaud, S.; Delacroix, H.; Beaune, P.; Laurent-Puig, P.; Laccourreye, O.; Brasnu, D.; Aggerbeck, L.; Barouki, R.
- Book ID
- 118655929
- Publisher
- Elsevier Science
- Year
- 2007
- Weight
- 52 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1744-7895
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## Abstract Fiftyβone patients (32 previously untreated, 19 previously treated) with advanced squamous cell carcinoma of the head and neck received a single course of combination chemotherapy consisting of high dose __cis__βplatinum (DDP), bleomycin (Bleo), Β± high dose methotrexate (MTX). Thirtyβth
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