P186 Cytokines stimulate growth of human articular chondrocytes in the absence of serum
β Scribed by S.J. Duguay; A. Parker; M. Zhang; S. Madden; B.J. Seymour
- Book ID
- 114350057
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 76 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1063-4584
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The objectives of this study were to establish a growth factor response profile for adult human articular chondrocytes, to determine whether this is unique for chondrocytes or influenced by the differentiation status of the cells, and to characterize growth factor interactions. It is shown that tran
## Background: Genetically engineered chondrocytes could be used to enhance cartilage repair. fibroblast growth factor 2 (fgf-2) is a mitogen for chondrocytes and may be a candidate for gene transfer approaches to stimulate chondrocyte proliferation. in the present study, we tested the hypothesis t