Hydrogen peroxide induces p16INK4a throu
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Gai E Guo; Li Wei Ma; Bin Jiang; Jie Yi; Tan Jun Tong; Wen Gong Wang
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Article
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2010
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John Wiley and Sons
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English
β 342 KB
## Abstract Elevation of p16^INK4a^ has been described as an important mechanism for hydrogen peroxide (H~2~O~2~)βinduced replicative senescence. However, the mechanisms underlying remain unknown. In this study, we demonstrate an important role of RNAβbinding protein AUF1βmediated mRNA turnover in