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P16 deletion and mutation analysis in human brain tumors

✍ Scribed by Fred G. Barker; Pengchin Chen; Felix Furman; Ken D. Aldape; Michael S.B. Edwards; Mark A. Israel

Book ID
110229055
Publisher
Springer US
Year
1997
Tongue
English
Weight
195 KB
Volume
31
Category
Article
ISSN
0167-594X

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## Abstract Chromosome 9p21 appears to harbor a tumor suppressor gene, as evidenced by deletions in this region in a variety of human primary tumors and cell lines. To map the deletion at 9p21 in bladder tumors, we analyzed DNA from 28 tumor and normal pairs at five microsatellite markers that flan