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Mutational analysis ofINI1in sporadic human brain tumors

✍ Scribed by Markus Weber; Florian Stockhammer; Ulrike Schmitz; Andreas von Deimling

Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
59 KB
Volume
101
Category
Article
ISSN
0001-6322

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## Abstract The Wilms' tumor 1 gene, __WT1__, encodes a zinc‐finger protein that is implicated in the development of Wilms' tumor. Mutant or aberrantly expressed WT1 isoforms have also been described in desmoplastic small round cell tumor, acute leukemias, mesothelioma, breast tumors and melanoma.