P130 Polymer-based tissue engineering of intervertebral disc nucleus pulposus tissue
โ Scribed by M. Endres; A. Enz; K. Neumann; M. Sittinger; A.A. Hegewald; C. Kaps
- Book ID
- 114350001
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 77 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1063-4584
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## Abstract Human intervertebral disc (IVD) degeneration often initiated from the human nucleus pulposus (hNP) with aging leading to IVD destruction and extracellular matrix (ECM) depletion. Previously, we have successfully employed transforming growth factorโฮฒ1 (TGFโฮฒ1) to promote chondrogenesis o
## Abstract Deuterium (^2^H) doubleโquantum filtered (DQF) NMR spectroscopy of nucleus pulposus (NP) tissues from human intervertebral discs is reported. The DQF spectral intensities, DQ buildโup rates, and DQFโdetected rotatingโframe spinโlattice relaxation times are sensitive to the degree of hyd
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