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P119 GENE EXPRESSION PROFILING TO PREDICT THE RESPONSE OF INFLIXIMAB IN PATIENTS WITH UC

โœ Scribed by I. Arjis; L. Van Lommel; K. Van Steen; G. De Hertogh; F. Schuit; K. Geboes; G. Van Assche; S. Vermeire; P. Rutgeerts


Book ID
119637106
Publisher
Oxford University Press
Year
2007
Weight
60 KB
Volume
1
Category
Article
ISSN
1873-9954

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Predictive value of epithelial gene expr
โœ Ingrid Arijs; Roel Quintens; Leentje Van Lommel; Kristel Van Steen; Gert De Hert ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 432 KB

Background: Infliximab (IFX) has become the mainstay of therapy of refractory Crohn's disease (CD). However, a subset of patients shows incomplete or no response to this agent. In this study we investigated whether we could identify a mucosal gene panel to predict (non)response to IFX in CD. Method