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P.115 Acceleration of protein degradation in C2C12 myotubes by hyperthermia and its mechanism

✍ Scribed by C. Ebisui; T. Tsujinaka; M. Yano; T. Morimoto; J. Fujita; K. Kan; M. Kishibuchi; A. Ogawa; S. Morita; M. Monden

Book ID: 117428240
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 237 KB
Volume: 14
Category: Article
ISSN: 0261-5614
DOI: 10.1016/s0261-5614(95)80264-9

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## Abstract Myostatin is a negative regulator of skeletal muscle mass. The pathways employed in modulating myostatin gene expression are scarcely known. We aimed to determine the signaling pathway of myostatin induction by a histone deacetylase (HDAC) inhibitor–trichostatin A (TSA) in differentiate