P112 Long-term results and predictors of therapeutic success in Parkinson’s disease treated with high-frequency stimulation in the subthalamic nucleus
✍ Scribed by R. Reese; J. Herzog; K. Knudsen; M.O. Pinsker; D. Falk; H.M. Mehdorn; J. Raethjen; G. Deuschl; J. Volkmann
- Book ID
- 118426287
- Publisher
- Elsevier
- Year
- 2011
- Tongue
- English
- Weight
- 36 KB
- Volume
- 1
- Category
- Article
- ISSN
- 2210-5336
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High-frequency stimulation of the subthalamic nucleus (STN) is a promising therapeutic approach in patients with severely disabling Parkinson's disease (PD). Whereas STN stimulation improves the cardinal signs of PD, little is known about the effects of STN stimulation on fine manual skills like han
## Abstract Stimulation of the subthalamic nucleus (STN) is an effective treatment for advanced Parkinson's disease (PD), but the medication requirements after implant are poorly known. We performed a long‐term prospective evaluation of 20 patients maintained at stable dopaminergic therapy for 5 ye
## Abstract Subthalamic nucleus (STN) stimulation improves motor disability and quality of life in patients with advanced Parkinson's disease (PD). Short‐term mortality is low, but little is known about long‐term mortality. We assessed mortality and causes of death in 171 consecutive PD patients tr
FIG. 1. (A) Location of neuronal recording sites in a sagittal projection onto the Schaltenbrand Wahren atlas at the average laterality of 22 mm. (B) Mean firing rates in GPi and GPe are increased after STN-HFS. Box plots show median (line within the box) as well as 10, 25, 75, and 90th percentiles