P103 Adapalene 0.1% gel shows a more rapid onset of action than tretinoin 0.025% gel in the treatment of acne vulgaris
โ Scribed by J. Meynadier; M. Alirezai; E. Grosshans; W. Waskiewicz; J.M. Mascaro; H. Torras; H.R. Marks; M. Poncet; V. Sorba; P. Soto; A. Clucas
- Book ID
- 118604542
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 126 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0926-9959
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A multicentre study was conducted to compare clinical safety and efficacy of adapalene 0.1% solution and tretinoin 0.025% gel, both topical treatments for acne, in a once-daily dosage regimen for 12 weeks. A total of 297 patients were enrolled by eight investigators in this randomized, investigator-
One hundred patients with acne vulgaris applied adapalene (Differin) 0.1% gel to one side of their face and tretinoin 0.025% cream to the other once a day for 4 weeks; the side of application was determined by randomization code. Patient tolerance (assessed as the side of the face least irritated by
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