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A comparison of the efficacy and safety of adapalene gel 0.1% and tretinoin gel 0.025% in the treatment of acne vulgaris: A multicenter trial

✍ Scribed by A Shalita; J.S Weiss; D.K Chalker; C.N Ellis; A Greenspan; H.I Katz; I Kantor; L.E Millikan; T Swinehart; L Swinyer; C Whitmore; M Baker; J Czernielewski


Book ID
117395486
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
505 KB
Volume
34
Category
Article
ISSN
1097-6787

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Comparison of adapalene 0Β·1% solution an
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A multicentre study was conducted to compare clinical safety and efficacy of adapalene 0.1% solution and tretinoin 0.025% gel, both topical treatments for acne, in a once-daily dosage regimen for 12 weeks. A total of 297 patients were enrolled by eight investigators in this randomized, investigator-

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The purpose of this meta-analysis was to determine if adapalene 0.1% gel (Differin) provided superior efficacy and better tolerability than tretinoin 0.025% gel in the treatment of acne vulgaris. All comparative studies, both published and unpublished, from the United States and Europe, that fulfill