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P1 Piperlongumine inhibits growth potential of gastric cancer cells by targeting PI3K/Akt/mTOR signaling pathway

โœ Scribed by Shrivastava, S.; Jeengar, M.K.; Thummuri, D.; Naidu, V.G.M.


Book ID
122288097
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
225 KB
Volume
50
Category
Article
ISSN
0959-8049

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Longitudinal inhibition of PI3K/Akt/mTOR
โœ Takayuki Ikezoe; Chie Nishioka; Kentaro Bandobashi; Yang Yang; Yoshio Kuwayama; ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 1006 KB

This study found that phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling was activated in human T-cell lymphotropic virus type I (HTLV-1)-infected leukemia cells. Rapamycin (1-100 nM, 48 h), the inhibitor of mTOR and its analog RAD001 (1-100 nM, 48 h)-induced gro