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P1-317: Apolipoprotein E genotype and variability in age at onset in sib-pairs with familial Alzheimer’s disease

✍ Scribed by Estrella Gomez-Tortosa; Sagrario Barquero; Manuel Baron; Raquel Ros; Sagrario Manzano; Maria J. Sainz; Carmen Almaraz; Pilar Gomez-Garre; Adriano Jimenez-Escrig


Book ID
118462766
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
67 KB
Volume
2
Category
Article
ISSN
1552-5260

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Apolipoprotein E genotypes and age of on
✍ Ephrat Levy-Lahad; Amnon Lahad; Ellen M. Wijsman; Thomas D. Bird; Dr Gerard D. S 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 339 KB 👁 2 views

## Abstract The effect of the apolipoprotein E (APOE) ϵ4 allele on age of onset was analyzed in two groups of families with early‐onset Alzheimer's disease (AD), (1) Volga German (VG) kindreds, in which AD is caused by an unknown locus and (2) early‐onset non‐VG families showing evidence of linkage