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P VII.1 - P VII.1 Induction of p21cip1/waf1 and concomitant G1 arrest are p53-independent in UVC-irradiated human fibroblasts

✍ Scribed by Martin Loignon; Raouf Fetni; Elliot Drobetsky


Book ID
114071668
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
130 KB
Volume
379
Category
Article
ISSN
0027-5107

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## Abstract __SDI1__ is an inhibitor of DNA synthesis that we isolated by expression screening cDNAs prepared from senescent, terminally nondividing human cells. Other groups then cloned this gene as a cyclin‐dependent kinase (cdk)‐interacting protein (CIP1, p21) that inhibits cdks; the gene was al