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p-Nitrobenzyl esters in the synthesis of peptides consisting of glycine and imino acids

โœ Scribed by V. G. Debabov; V. A. Shibnev

Book ID
112432144
Publisher
Springer
Year
1962
Tongue
English
Weight
309 KB
Volume
11
Category
Article
ISSN
1573-9171

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Amino acid esters of phenols as prodrugs
Amino acid esters of phenols as prodrugs: Synthesis and stability of glycine, ฮฒ-aspartic acid, and ฮฑ-aspartic acid esters of p-acetamidophenol
โœ Ildiko M. Kovach; Ian H. Pitman; Takeru Higuchi ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 670 KB

pH-rate profiles were calculated for the hydrolysis of the glycine (II), P-aspartic acid (III), and a-aspartic acid (IV) esters of pacetamidopbenol (I) at 25" and = 1.0 M. The hydrolysis of esters I1 and 111 occurred predominantly uia intermolecular reactions involving water, hydroxide ion, and the