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P-glycoprotein expression is associated with resistance to spontaneous in vitro apoptosis in AML

โœ Scribed by Pallis, M; Russell, N


Book ID
110054286
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
74 KB
Volume
13
Category
Article
ISSN
0887-6924

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p27 Kip1 , a cyclin-dependent kinase inhibitor, is a negative regulator of the cell cycle, and apoptosis is a genetically encoded program of cell death. To clarify the relationship between the cell cycle and apoptosis, we investigated expression of p27, cyclin D1 and apoptosis-related proteins (p53,