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Intracellular P-glycoprotein expression is associated with the intrinsic multidrug resistance phenotype in human colon adenocarcinoma cells

✍ Scribed by Stefania Meschini; Annarica Calcabrini; Elena Monti; Donatella Del Bufalo; Annarita Stringaro; Ersilia Dolfini; Giuseppe Arancia


Publisher
John Wiley and Sons
Year
2000
Tongue
French
Weight
978 KB
Volume
87
Category
Article
ISSN
0020-7136

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Multidrug resistance (MDR) in human cancer cells is multifactorial. Previously, we reported on the association between expression of P-glycoprotein (Pgp), the multidrug resistanceassociated protein (MRP), and the lung resistance protein (LRP) with the MDR phenotype in the NCI panel of 60 human cance