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P- and E-selectin-deficient mice are susceptible to cerebral ischemia–reperfusion injury

✍ Scribed by Sulpicio G. Soriano; Yanming F. Wang; Denisa D. Wagner; Paul S. Frenette

Book ID
114005099
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
361 KB
Volume
835
Category
Article
ISSN
0006-8993

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✍ Celine A. Beamer; Diane M. Brooks; Diana I. Lurie 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 616 KB

## Abstract We have demonstrated previously that the protein tyrosine phosphatase SHP‐1 seems to play a role in glial development and is upregulated in non‐dividing astrocytes after injury. The present study examines the effect of loss of SHP‐1 on the CNS response to permanent focal ischemia. SHP‐1