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Apolipoprotein E-Deficient Mice Have Increased Susceptibility To Focal Cerebral Ischemia

✍ Scribed by Laskowitz, Daniel T.; Sheng, Huaxin; Bart, Robert D.; Joyner, Kelly A.; Roses, Allen D.; Warner, David S.

Book ID
110078806
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
336 KB
Volume
0
Category
Article
ISSN
0271-678X

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## Abstract We have demonstrated previously that the protein tyrosine phosphatase SHP‐1 seems to play a role in glial development and is upregulated in non‐dividing astrocytes after injury. The present study examines the effect of loss of SHP‐1 on the CNS response to permanent focal ischemia. SHP‐1