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P-99 MnSOD, p53, XRCC1 polymorphisms and non-small cell lung cancer risk

✍ Scribed by Liu, Geoffrey; Zhou, Wei; Lynch, Thomas J.; Wang, Lisa I.; Park, Sohee; Wain, John C.; Su, Li; Christiani, David C.

Book ID
118571800
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
166 KB
Volume
41
Category
Article
ISSN
0169-5002

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## Abstract ## BACKGROUND Exogenous reactive oxygen species (ROS) induces DNA damage. Manganese superoxide dismutase (SOD2) catalyzes the dismutation of superoxide radicals, a major type of ROS, into hydrogen peroxide. __p53__ is a tumor suppressor gene, and X‐ray cross‐complementing group 1 (XRCC