Risk of non-small cell lung cancer and the cytochrome P4501A1 Ile462Val polymorphism
β Scribed by Jill Everland Larsen; Maree Louise Colosimo; Ian Anthony Yang; Rayleen Bowman; Paul Victor Zimmerman; Kwun Meng Fong
- Publisher
- Springer Netherlands
- Year
- 2005
- Tongue
- English
- Weight
- 186 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0957-5243
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## BACKGROUND Exogenous reactive oxygen species (ROS) induces DNA damage. Manganese superoxide dismutase (SOD2) catalyzes the dismutation of superoxide radicals, a major type of ROS, into hydrogen peroxide. __p53__ is a tumor suppressor gene, and Xβray crossβcomplementing group 1 (XRCC
## Abstract Lung cancer is one of the leading causes of cancer death worldwide. Tobacco smoking is the main risk factor for lung cancer. Less than 20% of smokers develop lung cancer in their lifetime, however, indicating individual variations in lung cancer risk. Proβinflammatory cytokines produced
Insulin-like growth factor binding protein-3 (IGFBP-3) inhibits the mitogenic and antiapoptotic activity of insulin-like growth factor (IGF) by blocking the binding of IGF to its receptor. However, under certain circumstances, IGFBP-3 can enhance the activity of IGF by protecting IGF from degradatio