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P-8-11 - The relationship between serotonin and melatonin in the rat pineal gland

โœ Scribed by P.J. Nathan; T.R. Norman; G.D. Burrows

Book ID
119177468
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
156 KB
Volume
6
Category
Article
ISSN
0924-977X

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Relationship between catecholamines and
Relationship between catecholamines and serotonin in sympathetic nerves of the rat pineal gland
โœ Zweig, Mark ;Axelrod, Julius ๐Ÿ“‚ Article ๐Ÿ“… 1969 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 724 KB

Sympathetic nerves of the pineal gland contain both serotonin and norepinephrine. Inhibition of norepinephrine synthesis with a tyrosine hydroxylase inhibitor, a-methyl-p-tyrosine (aMPT) , causes an elevation of pineal serotonin. The administration of dopamine or norepinephrine blocks the elevation