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P-454 Immunohistochemical detection of the receptor for urokinase plasminogen activator in hepatocellular carcinoma

โœ Scribed by T Akahane; M Ishii; H Ohtani; T Toyota

Book ID
113402338
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
112 KB
Volume
3
Category
Article
ISSN
0928-4346

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The urokinase-type plasminogen activator (uPA) and its receptor (uPAR) play an important role in tumour invasion. Previous studies have shown by RT-PCR that uPA and uPAR mRNAs are expressed in human hepatocellular carcinoma (HCC). Here, in situ hybridization, immunohistochemistry, and double immunoยฏ

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## Background: The authors found previously that plasma levels of urokinase-type plasminogen activator (upa) and its receptor (upar) were elevated in patients with bladder carcinoma and were associated with features of biologically aggressive disease. in the current study, they tested the hypothesi