Endothelin-1 acts as an autocrine growth
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Ryoji Tsuboi; Chiyo Sato; Chong-Ming Shi; Tsukasa Nakamura; Takeshi Sakurai; Hid
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Article
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1994
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John Wiley and Sons
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English
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Endothelin-I (ET-1) is an endothelium-derived 21 amino acid vasoconstrictor peptide possessing two intrachain disulfide bridges. Recently it has become evident that isoforms of ET (ET-l, -2, and -3) have a wide range of pharmacological effects in various tissues and act as autocrineiparacrine factor