Platelet-Derived Growth Factor Is an Autocrine Stimulator for the Growth and Survival of Human Esophageal Carcinoma Cell Lines
β Scribed by Young-Chau Liu; Shan-Chun Chen; Chungming Chang; Chuen-Miin Leu; Cheng-Po Hu
- Book ID
- 115602513
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 303 KB
- Volume
- 228
- Category
- Article
- ISSN
- 0014-4827
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π SIMILAR VOLUMES
Growth factors of the platelet-derived growth factor (PDCF) family have been thought to possess autocrine functions in certain neoplasms of mesenchymal and glial origin. This notion has been based on observations that these tumors express PDGF genes and produce PDGF-like growth factors. Correspondin
## Abstract In order to ascertain autocrine growth factors in esophageal carcinomas, we analysed expression of mRNAs and proteins for epidermal growth factor (EGF), transforming growth factorβΞ± (TGFβΞ±) and epidermal growth factor receptor (EGFR) in 6 esophageal carcinoma cell lines. Gene alteration