Oxytocin and vasopressin: Photoaffinity labeling of neurophysins, secretory granule hormone-binding proteins
β Scribed by David M. Abercrombie; Irwin M. Chaiken
- Book ID
- 118385439
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 747 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0163-7258
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## Abstract The synthesis of [^14^C]β10,11βEpoxyβ(2E,6E)βfarnesyl diazoacetate in one vessel, starting from [^14^C]βglyoxylic acid, is described. This compound is useful as a potential photoaffinity labeling agent for juvenile hormone binding sites.
The azidophenyl 6.7-epoxygeranyl ethers ruc4c and ruc-rld and the azidobenzoate ruc-6 were synthesized pAzidophenyl 6,7epoxygeranyl ether (rac4c) shows a high afhity to the juvenile hormone binding protein of the migratory locust, Locusro migraioria. Fast photolysis is observed upon irradiation at 2