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Oxygen isosteric derivatives of 3-(3-hydroxyphenyl)-N-n-propylpiperidine

✍ Scribed by Perrone, Roberto; Berardi, Francesco; Leopoldo, Marcello; Tortorella, Vincenzo; Lograno, Marcello D.; Daniele, Eugenia; Govoni, Stefano


Book ID
127113533
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
739 KB
Volume
35
Category
Article
ISSN
0022-2623

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## Abstract The motor effects of the partial dopamine agonist (–)‐3‐(3‐hydroxyphenyl)‐N‐n‐propylpiperidine [(–)‐3‐PPP, preclamol] were evaluated in nine patients with Parkinson's disease using a double‐blind, placebocontrolled design. (–)‐3‐PPP monotherapy had an antiparkinsonian effect in five of