𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Oxygen-induced changes in longitudinal relaxation times in skeletal muscle

✍ Scribed by Deirdre M. McGrath; Josephine H. Naish; James P.B. O'Connor; Charles E. Hutchinson; John C. Waterton; Chris J. Taylor; Geoffrey J.M. Parker

Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
664 KB
Volume
26
Category
Article
ISSN
0730-725X

No coin nor oath required. For personal study only.

✦ Synopsis

The objective was to measure the effect of 100% oxygen inhalation on T1 relaxation times in skeletal muscle. Healthy volunteers were scanned using three different MRI protocols while breathing medical air and 100% oxygen. Measurements of T1 were made from regions of interest (ROIs) within various skeletal muscle groups. Dynamic data of subjects breathing a sequence of air-oxygen-air allowed the calculation of characteristic wash-in and -out times for dissolved oxygen in muscle. Contrary to previous findings, a statistically significant decrease in T1 in skeletal muscle was observed due to oxygen inhalation. We report approximate baseline characteristic values for the response of skeletal muscle to oxygen inhalation. This measurement may provide new biomarkers for evaluation of oxygen delivery and consumption in normal and diseased skeletal muscle.

πŸ“œ SIMILAR VOLUMES

Changes in skeletal muscle gene transcri
Changes in skeletal muscle gene transcription induced by chronic stimulation
✍ Dr. Carol Brownson; Dr. Harvey Isenberg; Dr. Wendy Brown; Dr. Stanley Salmons; D πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 773 KB

The mRNA products of four genes, carbonic anhydrase 111 (CAIII), fast myosin heavy chain (MHCf), actin and glyceraldehyde-3-phosphate dehydrogenase (GAPDH), were assayed by Northern and slot-blot analysis in rabbit tibialis anterior and extensor digitorurn longus muscles that were subjected to elect

Alterations of the proton-T2 time in rel
Alterations of the proton-T2 time in relaxed skeletal muscle induced by passive extremity flexions
✍ Jens Rump; JΓΌrgen Braun; Sebastian Papazoglou; Matthias Taupitz; Ingolf Sack πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 386 KB

## Abstract ## Purpose To demonstrate reciprocal changes of the apparent proton‐T~2~ time in the biceps and triceps due to passive contraction and extension of the muscle fibers. ## Materials and Methods The contraction state of the upper arm muscles of six healthy volunteers was passively chang