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Oxygen-Dependent Gene Expression in Development and Cancer: Lessons Learned from the Wilms’ Tumor Gene, WT1

✍ Scribed by Scholz, Holger; Kirschner, Karin M.


Book ID
120161903
Publisher
Frontiers
Year
2011
Tongue
English
Weight
713 KB
Volume
4
Category
Article
ISSN
1662-5099

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The expression of the Wilms tumor suppressor gene WT1 is largely restricted to elements of the developing urogenital system. In the fetal kidney, WT1 transcripts are present at low levels in the condensing mesenchyme and at much higher levels in differentiating glomerular epithelium and are not dete