Coupling phosphoryl transfer and substra
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Scot A. Lieser; Brandon E. Aubol; Lilly Wong; Patricia A. Jennings; Joseph A. Ad
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Article
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2005
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Elsevier Science
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English
⚖ 483 KB
Protein kinases control cell signaling events through the ATP-dependent phosphorylation of serine, threonine and tyrosine residues in protein targets. The recognition of these protein substrates by the kinases relies on two principal factors: proper subcellular co-localization and molecular interact