## Abstract A cyclin‐dependent kinase, Cdk2, catalyzes the transfer of the γ‐phosphate from ATP to a threonine or serine residue of its polypeptide substrates. Here, we investigate aspects of the reaction mechanism of Cdk2 by gas‐phase density functional calculations, classical molecular dynamics,
Benchmark calculations on models of the phosphoryl transfer reaction catalyzed by protein kinase A
✍ Scribed by Manuel Montenegro; Mireia Garcia-Viloca; Àngels González-Lafont; José M. Lluch
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 819 KB
- Volume
- 124
- Category
- Article
- ISSN
- 1432-2234
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