Recently, the close relation between oxidized low density lipoprotein (Ox-LDL) and the progression of glomerular injury has been demonstrated. The nitric oxide (NO) pathway in glomerular mesangial cells may be a potential target for the adverse eects of Ox-LDL in the development of glomerular injury
✦ LIBER ✦
Oxidized high-density lipoprotein enhances inflammatory activity in rat mesangial cells
✍ Scribed by Miao Zhang; Xiang Gao; Jianxiang Wu; Dongmei Liu; Houan Cai; Lili Fu; Changlin Mei
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 409 KB
- Volume
- 26
- Category
- Article
- ISSN
- 1520-7552
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## Abstract Platelet‐derived growth factor‐BB (PDGF‐BB) has been implicated in the pathogenesis of progressive glomerulonephritis (GN). Previous studies have reported that PDGF‐BB stimulates mesangial cells (MCs)‐induced collagen matrix remodeling through enhancement of α1β1 integrin‐dependent migr