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Oxidized apurinic/apyrimidinic sites formed in DNa by oxidative mutagens

โœ Scribed by Lawrence F. Povirk; Robert J. Steighner

Book ID
113193701
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
831 KB
Volume
214
Category
Article
ISSN
0027-5107

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The excision repair of DNA damaged by physical or chemical agents may produce either apurinic/apyrimidinic (AP) sites or single-strand breaks (SSB) in the DNA. Alkaline-sucrose gradient sedimentation and alkaline elution, techniques generally used for the study of DNA repair which depend upon high p