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Repair of apurinic/apyrimidinic sites in single-stranded DNA initiated by tyrosyl-DNA phosphodiesterase 1

โœ Scribed by Lebedeva, N. A.; Rechkunova, N. I.; Lavrik, O. I.

Book ID
125395910
Publisher
SP MAIK Nauka/Interperiodica
Year
2014
Tongue
English
Weight
313 KB
Volume
455
Category
Article
ISSN
1607-6729

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The excision repair of DNA damaged by physical or chemical agents may produce either apurinic/apyrimidinic (AP) sites or single-strand breaks (SSB) in the DNA. Alkaline-sucrose gradient sedimentation and alkaline elution, techniques generally used for the study of DNA repair which depend upon high p