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Oxidative stress reduces the muscarinic receptor function in the urinary bladder

โœ Scribed by Rik de Jongh; Guido R.M.M. Haenen; Gommert A. van Koeveringe; Miriam Dambros; Jo G.R. De Mey; Philip E.V. van Kerrebroeck


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
254 KB
Volume
26
Category
Article
ISSN
0733-2467

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We have previously shown that bladder urothelium of people living in the cesium-137 ( 137 Cs)-contaminated areas of Ukraine demonstrates accumulation of stable p53 and p53 mutational inactivation, preferentially through G:C to A:T transition mutations at CpG dinucleotides, with a codon 245 hot spot.