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Oxidative Stress in the Induction of Apoptosis Mediated by Protein-Kinase A in Glucose-Deprived Hepatocytes

✍ Scribed by Anabela Ferretti; Mattaloni Stella; Justina Ochoa; María Cecilia Larocca; Cristián Favre

Book ID
113631557
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
383 KB
Volume
49
Category
Article
ISSN
0891-5849

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## Abstract 5‐Lipoxygenase (5‐LOX) is a key enzyme catalyzing arachidonic acid to form leukotrienes. We have reported that ischemic‐like injury activates 5‐LOX in PC12 cells; however, the mechanisms are unknown. To determine whether ischemic‐like injury activates 5‐LOX mediated by oxidative stress