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Oxidative stress enhances phosphorylation of p53 in neonatal rat cardiomyocytes

✍ Scribed by Xilin Long; Michael J. Goldenthal; José Marín-García


Book ID
106458245
Publisher
Springer
Year
2007
Tongue
English
Weight
263 KB
Volume
303
Category
Article
ISSN
0300-8177

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Oxidative stress to mammalian cells causes cellular damage and triggers inducible cellular responses leading to cell death by apoptosis. In this paper, we report that p53 was required for programmed cell death induced by oxidative stress in both mouse and human cells and that p53 transactivation was