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Artemis is a negative regulator of p53 in response to oxidative stress

โœ Scribed by Zhang, X; Zhu, Y; Geng, L; Wang, H; Legerski, R J

Book ID
109970897
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
454 KB
Volume
28
Category
Article
ISSN
0950-9232

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Oxidative stress to mammalian cells causes cellular damage and triggers inducible cellular responses leading to cell death by apoptosis. In this paper, we report that p53 was required for programmed cell death induced by oxidative stress in both mouse and human cells and that p53 transactivation was