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Oxidative Stress and Upregulation of Mitochondrial Biogenesis Genes in Mitochondrial DNA-Depleted HeLa Cells

✍ Scribed by Soledad Miranda; Rocio Foncea; Javier Guerrero; Federico Leighton

Book ID
115583687
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
251 KB
Volume
258
Category
Article
ISSN
0006-291X

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## Abstract Here, we sought to clarify the comprehensive cellular response to transcription factor E2F1 expression using short interfering RNA (siRNA)‐mediated gene silencing to examine the roles of E2F1. For this purpose, we analyzed global gene expression changes in E2F1 knockdown HeLa cells, whe