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Oxidative DNA Damage Induced by Ethanol in Mouse Peripheral Leucocytes

โœ Scribed by Lei Guo; Jing Yu Yang; Chun Fu Wu


Book ID
111316514
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
187 KB
Volume
103
Category
Article
ISSN
1742-7835

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We compared the potential of asbestos and man-made fibers to attack DNA by the determination of the yield of 8-hydroxy-2'-deoxyguanosine (8-OH-dGuo) under several in vitro conditions. Asbestos induced 6.6-99.8 of 8-OH-dGuo per 10(5) dGuo in calf thymus DNA after 20 h of incubation, while the levels