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Oxidative degradation of cationic metalloporphyrins in the presence of nucleic acids: a way to binding constants?

✍ Scribed by Ding, Li; Bernadou, Jean; Meunier, Bernard


Book ID
126294052
Publisher
American Chemical Society
Year
1991
Tongue
English
Weight
720 KB
Volume
2
Category
Article
ISSN
1043-1802

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## Abstract The interaction of fluoroquinacrine, 3‐fluoro‐7‐chloro‐9‐(diethylamino‐1‐methylbutyl‐amino)acridine, with poly(A), DNA, and tRNA has been investigated by monitoring changes in the ^19^F‐nmr properties, the fluorescence, and the optical absorbance of the drug. The changes in the properti