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Cooperativity in the binding of the cationic biocide polyhexamethylene biguanide to nucleic acids

โœ Scribed by Michael J Allen; Andrew P Morby; Graham F White


Book ID
116288345
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
272 KB
Volume
318
Category
Article
ISSN
0006-291X

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Affinity coelectrophoresis (ACE) is a technique for characterizing ligand/nucleic acid binding interactions under equilibrium conditions. It is used here to characterize the protamine clupeine \(\mathrm{Z}\) binding to several DNA fragments in order to define the use and limitations of ACE for ligan