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Oxidative damage to DNA, p53 gene expression and p53 protein level in the process of aging in rat brain

โœ Scribed by Jolanta Dorszewska; Zofia Adamczewska-Goncerzewicz


Book ID
116860909
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
135 KB
Volume
139
Category
Article
ISSN
1569-9048

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Exposure of mammalian cells to genotoxic agents evokes a complex cellular response. An ordered series of molecular events is necessary to sense DNA damage, transduce the signal, and ultimately delay the cell cycle or trigger apoptosis. Recently, we have shown that BTG2/TIS21 gene expression was indu