𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Modifications of p53 and the DNA Damage Response in Cells Expressing Mutant Form of the Protein Huntingtin

✍ Scribed by Jennifer L. Illuzzi; Cassie A. Vickers; Eric B. Kmiec


Book ID
107575453
Publisher
Humana Press Inc
Year
2011
Tongue
English
Weight
567 KB
Volume
45
Category
Article
ISSN
0895-8696

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


BTG gene expression in the p53-dependent
✍ Ulrich Cortes; Caroline Moyret-Lalle; Nicole Falette; Cyril Duriez; Fatiha El Gh πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 250 KB

Exposure of mammalian cells to genotoxic agents evokes a complex cellular response. An ordered series of molecular events is necessary to sense DNA damage, transduce the signal, and ultimately delay the cell cycle or trigger apoptosis. Recently, we have shown that BTG2/TIS21 gene expression was indu

p53 Protein expression in squamous cell
✍ Marit ScheistrΓΈen; Claes TropΓ©; Erik O. Pettersen; Jahn M. Nesland πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 93 KB πŸ‘ 2 views

## Background: The objective of the study was to evaluate the pathogenetic and prognostic value of p53 protein expression in squamous cell carcinoma of the vulva. ## Methods: The clinical data in charts of 167 patients with international federation of gynecology and obstetrics (figo) stages i-iii

Aberrant p53 alters DNA damage checkpoin
✍ Katharine H. Wrighton; Cecilia M. PrΓͺle; Andrew Sunters; W. Andrew Yeudall πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 1006 KB

## Abstract The p53 tumor suppressor protein is a critical mediator of cell cycle arrest and apoptosis in response to genotoxic stress. Abrogation of p53 function is a major feature of tumor development and may result in a compromised DNA‐damage response. In our study, we examined the effect of exp