Oxidative Cleavage of Triethylenetetramine (trien) to Yield Diethylenetriamine (dien): Structure of the MnII/MnIII Heptanuclear Complex [Mn7(trien)2(dien)2O4(OAc)8](PF6)4·2H2O

✍ Scribed by Dr. Rajumati Bhula; Dr. David C. Weatherburn

• Publisher: John Wiley and Sons
• Year: 1991
• Tongue: English
• Weight: 261 KB
• Volume: 30
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.199106881

✦ Synopsis

The stereoselective reaction sequences presented here enable the synthesis of numerous heterocyclic ring systems. Depending upon the oxime system used, the reaction sequences lead with ring expansion to products of the azepane type or by direct cyclization to products of the perhydroquinoline type, whereby the functionalization of the heterocycle formed is determined by the allylsilane-substituent. Considering the number of steps involved in a one-pot reaction the yields of 40-50% obtained are very good. An analogous reaction could be carried out with cyclopentanone, however we have not yet been able to establish the relative configurations of the products.