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Oxidative cleavage of 1,2-diols with N-iodosuccinimide

โœ Scribed by Beebe, Thomas R.; Hii, Paul; Reinking, Patty


Book ID
115480205
Publisher
American Chemical Society
Year
1981
Tongue
English
Weight
362 KB
Volume
46
Category
Article
ISSN
0022-3263

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N-iodosuccinimide mediated oxidative cle
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Vbinal, monoprotected dials are cleaved to mixed acetals and carbonyl compounds upon treatment with N-bdosucclnimfde in the presence of light, base, and methanol. N-bdosucdnimide (NIS) has been shown to bs a versatile oxidant for the alcohol functtonaf groupP lnftially NIS converts the alcohol to a