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N-iodosuccinimide mediated oxidative cyclization of mono-t-butyldimethylsilylated diols

โœ Scribed by Chriss E. McDonald; Thomas R. Beebe; Mark Beard; Doug McMillen; Daniel Selski


Book ID
104232952
Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
210 KB
Volume
30
Category
Article
ISSN
0040-4039

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N-iodosuccinimide mediated oxidative cle
โœ Chriss E. McDonald; Harald Holcomb; Todd Leathers; Francis Ampadu-Nyarko; James ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 257 KB

Vbinal, monoprotected dials are cleaved to mixed acetals and carbonyl compounds upon treatment with N-bdosucclnimfde in the presence of light, base, and methanol. N-bdosucdnimide (NIS) has been shown to bs a versatile oxidant for the alcohol functtonaf groupP lnftially NIS converts the alcohol to a