Oxidative Addition of 4-Hydroxycoumarin to Alkenes. An Expeditious Entry to 2,3-Dihydro-4 H -furo-[3,2- c ][1]benzopyran-4-ones 1
โ Scribed by Appendino, Giovanni; Cravotto, Giancarlo; Palmisano, Giovanni; Annunziata, Rita
- Book ID
- 118175980
- Publisher
- Taylor and Francis Group
- Year
- 1996
- Tongue
- English
- Weight
- 404 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0039-7911
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๐ SIMILAR VOLUMES
we describe a convenient and general method for the preparation of 2,3-dihydro-2-niuo-3-phenyl-4H-furo[3,2-c][l]~~opy~-4-ones from cl-hydroxycoumarin and (2-chloro-2-nitroethenyl)benzenes in the presence of potassium fluoride. Using the same starting materials and by replacing potassium fluoride wit
Methyl 2-(4-hydroxybutyl)-4-oxo-4~-1-benzopyran-3-carboxylate 6 1s transformed mto the sproacetals 13 and 14 (ratio 5 1) vw treatment with mdomethane&otassmm carbonate, the process mvolvmg sequenaal mtramolecular conjugate addmon and enolate alkylafion The 2,3-epoxlde 7 derived from 6 undergoes spuw