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Oxidations by copper metalloenzymes and some biomimetic approaches

✍ Scribed by Marc Fontecave; Jean-Louis Pierre

Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
326 KB
Volume
170
Category
Article
ISSN
0010-8545

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✦ Synopsis

This paper illustrates the various aspects of the reactivity of the Cu(II )-Cu(I ) system in biological systems, with one example of an enzymatic reaction in which Cu(II ) alone is oxidizing enough to carry out the reaction (superoxide dismutase), one example in which a Cu(II )-bound peroxo intermediate is the active species (tyrosinase) and the examples of galactose oxidase and copper amine oxidases in which Cu(II ) is associated with a redox active organic cofactor. In some cases, we will show some illustrations of biomimetic approaches developed in our laboratories, aimed at a better understanding of reaction mechanisms and at an original design of new catalysts with potential applications in synthetic chemistry. Some comments are given concerning the respective features of copper and iron.

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Electron transfer. 102. Some oxidations
Electron transfer. 102. Some oxidations by bromite (BrO2βˆ’)
✍ Amrit K. Jhanji; E. S. Gould πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 465 KB

## Abstract Bromite, BrO~2~^βˆ’^, in aqueous carbonate or borate buffers (pH 9–11), reacts rapidly with H~3~AsO~3~, with the tartrate complex of Sb(III), and with the EDTA complexes of Sn(II) and U(IV). Each reaction yields Br^βˆ’^, even when BrO~2~^βˆ’^ is taken in excess. Reaction rates with Sb(III) an